Comedienne Karen Dunbar will host the event at the Clyde Auditorium and it will feature singers Susan Boyle and Darius Campbell and television presenter Carol Smillie.
There is still time to buy tickets for the Prince and Princess Of Wales Hospice 30th Anniversary Variety Performance, which is the latest step in the Brick By Brick campaign, backed by the Evening Times, to raise £15 million to create a new facility next to Bellahouston Park.
The first gala variety show was held 30 years ago when the hospice first moved into Carlton Place and was attended by 1800 guests, including the Prince and Princess, at the King's Theatre.
Tomorrow's event is expected to attract an audience of thousands and will include performances by vocal quartet Amore - Royal College of Music graduates who bring modern-day opera to the masses - performers from the Royal Conservatoire of Scotland, and dance act Gymtasia Evolution.
Fans of television's The Voice will get a chance to hear Barbara Bryceland and Tallia Storm, and Britain's Got Talent's Edward Reid.
Owen Paul, the Scottish singer who had a 1980s hit with My Favourite Waste Of Time, will be performing in his home city.
He said: "I'm delighted to be performing again in Glasgow for such a brilliant cause.
"My aunt Nancy was cared for at the hospice during the last part of her life and if they need funds for a new building, I am more than happy to help even just in a small way."
The Brick by Brick appeal will help raise the remaining £15m of the £20m. It will offer improved services and let the hospice lower the age limit to patients it treats to those aged 15 and above.
Tickets, priced from £19, can be picked up at the door after being bought from TicketSoup on 0844 3954000 or through the website www.ticketsoup.com/ 30thanniversary.