The Hoops went down 2-1 against Aberdeen last Saturday despite taking an early lead through Anthony Stokes, and the manager has urged his side to continue their march towards a third successive title.
"Obviously, I´m looking for a reaction," he told this week's Celtic View. "We might need to look at other players to freshen things up a bit as we looked a bit flat for some reason and I don´t know why, as that hasn´t been evident in the last month or so.
"We have a title to win and an unbeaten record to preserve but we did want the Scottish Cup, and we did prepare very well for it, though the performance didn't reflect it, and that´s something we need to look at."
Charlie Mulgrew could return to the reckoning after missing out going head-to-head with his former employers with a calf injury.
"I don´t want to make too many radical changes as we have been going well, and hopefully Charlie will be fit as well," said the manager. "He got a bang on the calf last Friday and we gave him as long as possible but he couldn't get through it.
"Adam Matthews got a good 90 minutes against Aberdeen and needs more game-time. Stefan Johansen needs more games and Leigh Griffiths will come into contention along with Derk Boerrigter.
"We just have to be relentless now and win the title. We have to get that out our system as quickly as possible. We can´t get it back and that´s a regret that myself and the players have. There is still a lot of progress to be made, obviously, off the back of that performance.
"We have a title to win and an unbeaten record to preserve and that´s our sole focus now for the rest of the season."