The three-day event in Perthshire will see stars Paolo Nutini, Calvin Harris and Pharrell Williams wow the crowds.
The sun was shining as they left, but rain is forecast for Saturday and Sunday.
Karly Porter, 23, from Mosspark, is heading to Balado with friends Conor Harte, 25, and Richard Spence, 26, both from Govan.
She said: "I'm looking forward to seeing Calvin Harris and Jake Bugg and we don't care about the rain. What's a bit of rain? We're from Glasgow."
Friends Julia Chan, 18, and Monique Sarwar, 17, from Linwood, want to see Biffy Clyro. "We love them," said Julia, "we like Paolo too."
Michaela McEleney, 17, from Lenzie and Olivia Watson, 17, from Cambuslang were loaded down with rucksacks.
Olivia said: "We've got tents and lots of food and drink so even if it rains we'll still have fun."