Keira Knightley's Broadway debut was interrupted when a member of the audience shouted at the actress and threw a bouquet of flowers at the stage before being escorted from the theatre.

Knightley, who plays the title character in the play Therese Raquin, was on-stage with Gabriel Ebert when the disturbance took place at the Studio 54 Theatre.

The Theatre is same location where last year actor Shia LaBeouf was handcuffed during a performance of Cabaret for yelling obscenities.

Jessica Johnson, who represents the Roundabout Theatre Company, says the safety of actors and audiences is taken very seriously and extra security would be added.