Over the next five years Scottish Water is to invest more than £250million to improve the river quality of the Clyde and the natural environment surrounding it.
Water bosses say several jobs will be created, including about 50 apprenticeships, while around 500 jobs will be supported by the scheme.
They say the aim is to secure a waste water network with a capacity to help the whole Greater Glasgow area continue to develop and grow.
The long-term project – to alleviate sewer flooding and deal with the effects of increased rainfall and climate change – will last 20 years in total, with the first phase in the next five years.
Guests including Deputy First Minister Nicola Sturgeon and Councillor Gordon Matheson, leader of Glasgow City Council, were due to join Scottish Water chiefs for this morning's launch at Glasgow Science Centre.
Speaking ahead of the event, Geoff Aitkenhead, Scottish Water's Asset Management Director, said: "Scottish Water will be announcing a massive investment to transform Glasgow's waste water infrastructure and make it fit for the 21st century."