A broken down lorry was blocking one lane eastbound between junctions 25 and 24, while the M8 remains closed westbound at junction two following a serious accident.
An earlier breakdown near junction 15, which closed two lanes of the westbound carriageway, has now been cleared.
Traffic Scotland tweeted: "Reports now of an accident on the E/B between J3 and J2, within rubbernecking congestion. Lane one (Of two) is closed
" Eastbound between J25 and J24 there is a broken down lorry blocking lane one (of three).
Traffic Scotland is advising commuters trying to travel to Glasgow from Edinburgh to delay their journey.
It tweeted: "M8 is closed W/B at J2, likely to remain closed for some time. No access to the M8 from #M9 at Newbridge. Lengthy Delays on all approaches.
"Already lengthy delays back to Hermiston Gait Roundabout due to the closure of the #M8 W/B at J2 Newbridge and on the #M9. One to avoid!
"If you're trying to get out of Edinburgh this evening, probably best either waiting or using the train. Long Q's on the A71, A8 and Newbridge."
Sections of the motorway were closed earlier today after a milk tanker broke down near junction 20.