Extra staff have been brought in to help deal with the almost 110,000 passengers who are due to pass through the terminal by Monday night, with airlines laying on extra flights.
The exodus has been triggered by the October week school holiday.
Some youngsters got last week off and flew out of Glasgow last weekend.
But the majority of schools are shut next week and the staggered holidays mean thousands of holidaymakers will be jetting in and out of the airport this weekend.
Favourite hotspots for families before the start of another Scottish winter are Dubai, the Canary Islands, Turkey, the Balearics and Florida, where weekend temperatures are predicted to vary between a low 23C to a high 35C.
Meanwhile, here in Glasgow, the forecast is wet and cloudy with a high of 15C.
Francois Bourienne, commercial director at the airport, said: "The October holiday weekend is the busiest of the year for our airlines. For many travellers, their holiday begins the moment they arrive at the airport.
"This year we expect to welcome more passengers than last and we will be creating a tremendous buzz in the terminal so that families can get into the holiday spirit as they pass through the airport."
And the school break set to be a cash generator for low cost airline Jet2 and sister firm Jet2holidays.
Chief Executive Steve Heapy said: "This is going to be our busiest October half term weekend yet at Glasgow Airport. More than 7000 passengers are due to fly with us, an increase of 16% on last year."
The bumper weekend traffic comes on the back of a sustained period of passenger growth at the airport since January, 2011.