City dwellers are more likely to die from coronary heart disease (CHD) than anyone else in the country and most other places in the UK.
From 2009-2011 Glasgow had 128 deaths per 100,000 people, the third highest rate in the UK.
It was followed by West Dunbartonshire with 124 deaths and Dundee at 112.
Moray had the lowest number of deaths of any local authority area in Scotland at 56 and was the second lowest in the UK, just below Kensington and Chelsea which had 39.
The highest number of heart deaths in the UK was in Tameside in Greater Manchester, followed by Ballymoney in Northern Ireland.
The figures were released by the British Heart Foundation as the charity launched a new UK-wide TV campaign in the battle to beat heart disease.
The TV advert features the devastating moment when Bolton Wanderer footballer Fabrice Muamba suffered a mid-game cardiac arrest.
Professor Peter Weissberg, BHF Medical Director, said: "These latest figures expose staggering inequalities in deaths from heart disease across Scotland.
"We urgently need the nation to unite behind our quest to fund research to eradicate this deadly disease wherever it strikes."
BHF Professor Mark Kearney, a researcher, cardiologist and face of the TV advert, said: "Heart disease devastates too many lives.
"But medical research costs money and the BHF urgently needs support to rid the UK of heart disease and the misery it brings."
Leo Fernandes, a painter and decorator who had a heart attack when he was 46 and features in the TV advert, said: "After my triple bypass I was terrified about not being able to be who I was before.
"I felt like an old man.
"The truth is, heart disease affects everyone."
The BHF is calling for people to text FIGHT to 70123 and give £3 or make a donation by visiting bhf.org.uk