Roads bosses took action after receiving reports that a higher than expected number of cars displaying blue badges were parking in some city centre streets.
They sent out enforcement officers and located 65 vehicles displaying disabled badges and caught 12 drivers using them illegally.
Others were seen driving off from a disabled space when they spotted enforcement officers.
The names of motorists found illegally using a blue badge are passed to the Procurator Fiscal for possible court action.
Genuine badge holders who were also checked all said they supported the crackdown.
Glasgow, along with Edinburgh and Aberdeen councils, are presently pushing for tougher penalties for disabled badge misuse.
Some councils are insisting it should be branded as fraud rather than a motoring offence.
City council land and environment spokesman Alistair Watson said: "We recognise there are many genuine badge holders out there. However there is evidence that abuse of blue badges is taking place.
"This can have a significant impact on traffic movement through the reduced availability of parking bays to the public, but more importantly, to the genuine badge holders.
"We also knew genuine badge holders were finding it difficult to find parking so we organised the operation to crack down on misuse.
"The rules on the misuse of blue badges are very clear. It is an offence to use a blue badge unless it is for the benefit of the badge holder. People who abuse blue badges are depriving disabled people of opportunities the rest of society take for granted.
"We are fully aware of the ongoing problem and will continue to actively monitor the use of badges."
Identifying badges being used illegally is difficult as the parking attendant has to be present when a driver leaves or returns to his or her vehicle.
Because of time constraints, attendants are not able to wait indefinitely for the driver to return to the vehicle.