The mystery surrounding a European police match-fixing investigation into a Champions League game in England has deepened after it emerged neither the Football Association nor UEFA were aware of any such probe.

Rob Wainwright, director of Europol – the European Union's law enforcement agency, said the match which took place "in the last three to four years" was one of 380 under investigation.

Europol said a total of 425 match officials, club officials, players, and serious criminals, from more than 15 countries, are suspected of being involved in attempts to fix matches.

Wainwright refused to name the English Champions League match due to "ongoing judicial proceedings" – and the FA, which as the governing body in the country should be alerted, is also at a loss to know which one.

A spokesman for the Football Association said: "The FA are not aware of any credible reports into suspicious Champions League fixtures in England, nor has any information been shared with us."

It is understood UEFA is similarly unaware of an investigation. A Europol spokesman said he was unable to comment when asked why neither the FA nor UEFA had been told.

Investigators said an Asia-based syndicate is behind the fixing of 380 matches, along with World Cup and European Championship qualifiers and several "top matches in European leagues".

Wainwright said: "This is the work of a suspected organised crime syndicate based in Asia and operated with criminal networks around Europe.

"It is clear to us this is the biggest-ever investigation into suspected match-fixing in Europe. It has yielded major results, which we think have uncovered a big problem for the integrity of football in Europe."