Many queued for more than an hour to apply for their share of the one million tickets available across all the Commonwealth Games events including the opening and closing ceremony.
Members of the public took to Twitter to share their excitement, saying they had bid for hundreds of pounds worth of tickets.
One person wrote: "My name's in the hat for £500 of @Glasgow2014 tickets. Fingers crossed for the rugby and Opening Ceremony."
Other people used the social media website to share their frustrations at not being able to access the site without delays.
Many commented on the long online queues and shared the times they had been waiting, while others celebrated successful applications.
A spokesman from Glasgow 2014 confirmed that there was a "very high level of demand" on the website, yesterday.
He said: "The website is up and running and thousands of people have already completed and submitted their applications.
"Due to the very high levels of demand, however, some people may have to queue, although waiting times are coming down."
One million tickets across 17 sports over 11 days of competition are up for grabs, with two-thirds priced at £25 of less.
The four-week ticketing phase closes on Monday, September 16 and applications can be made online or by post.
It makes no difference whether fans apply on the first day or the last, as organisers have promised the same opportunity to enter the ballot.
Ty Speer, deputy chief executive of Glasgow 2014, said the ticketing system was designed to deal with high demand which they expected on the first day.
He said: "Day one is always really busy, no matter how many times you put out the message that you can apply on any day.
"We know that some people are really excited and want to be in on day one and we understand that.
"We expected that day one would be very busy, we know that there will be queues on day one, but that will things will begin to smooth out over the next couple of days.
"We do believe that the system is very strong, we have kept it as simple as it could be, so we have minimised complexity everywhere we can so we are pretty confident it is going to get the job done."
To mark the launch of the ticketing programme, Olympic swimmer Michael Jamieson dived into the newly-refurbished 50m pool at Tollcross International Swimming.
It was the first time the London 2012 silver medallist had swum in the pool since its £14million revamp.
Michael, 25, from Robroyston, who is hoping to win Gold on the first night of competition next year, trained in the pool as a youngster with the City of Glasgow Swim Team.
He shared the historic moment with swimmers from his former school, Glasgow School of Sport.
Nearby members of the public swam while young swimmers took part in swimming lessons.
Many of the Games venues are already being used by residents in the run up to Glasgow 2014.
Leader of Glasgow City Council, councillor Gordon Matheson said he was confident the seats would be packed with Glaswegians during the Games.
He said: "The key thing about Tollcross is that it is world class but it is currently open and is being used by the people of Glasgow.
"All of these venues are owned by the people of the city and next year we will lend them to elite athletes from across the Commonwealth and we will put on the finest Games that there has ever been.
"These are Glasgow's Games. In 2007 the Games were awarded and the envelope was opened and an announcement was made that the 2014 Commonwealth Games were awarded to the City of Glasgow, from that moment, the people of Glasgow claimed this as their own, so I have no doubt whatsosever that the venues are going to be packed full of Glaswegians."
Deputy First Minister Nicola Sturgeon said the anticipation was building ahead of the Games.
She said: "I live in Glasgow, I am a Glasgow MSP and I think there is a genuine sense of excitement about the Games so I am confident there will be a strong demand for tickets.
"Obviously, events like the ones that will be in Tollcross are particularly popular events, but I think every single event and competition is going to have people that want to be there and see it and just take part in it.
"The atmosphere in Glasgow, I think, will be absolutely tremendous."
To apply for tickets, visit www.glasgow2014.com or pick up the Official Ticketing Guide which contain postal application forms.
These are available at leisure centres, libraries, museums and transport hubs across Scotland.