The city is one of only 10 locations across the UK to host the Women's Running 10K in 2014.
The Glasgow leg of the run, which will be held on Saturday, September 6, will start and finish in Strathclyde Country Park.
It has been organised by Women's Running magazine, which aims to inspire females to improve their running.
Editor Christina Macdonald said: "We received so much positive feedback from the first three events this year we decided to extend the series to new areas of the UK in 2014.
"Our aim is to inspire and motivate women of all ages and abilities to run and these events provide the framework to make that happen.
"All women taking part will be encouraged to achieve their own personal goals, from simply getting round a 10K course to achieving a personal best, and we will be there to help them every step of the way."
The event is suitable for women of all abilities and pacers will be on hand to run with participants to help them achieve their target time.
A team of pacers will target times of 50, 55 and 60 minutes and one will work with a run/walk group aiming for around 70 minutes.
Ms Macdonald said: "We want to provide the support for as many women as possible to start running or help them to take their running to the next level.
"Offering training plans, combined with access to experienced runners in the form of pacers on race day, is extremely important to us."
As well as hosting the Women's Running event Strathclyde Park, to the south of the city, will also host the Commonwealth Games triathlon.
The new running event is the latest in a series aimed at women who have taken up the sport.
Cancer Research UK holds an annual Race for Life in the city, which is a women-only event that raises money for research. And in May this year, thousands of women braved pouring rain to take part in the UK's largest all-female 10K through Glasgow.
The Bupa Great Women's 10K, saw 5895 athletes and novices pound the roads and pavements in the South Side of the city.
For more information, to get training tips, or to enter the Women's Running 10K go to www.wr10k.co.uk