Organisers are promising a wild weekend to say goodbye to the Balado site, where the festival has been held for the past 18 years.
Festival Director Geoff Ellis was there to open the campsite gates yesterday afternoon.
He said: "The moment we open the campsite gates and welcome the first campers to the festival is my favourite moment of the weekend every year, and it was even more poignant this year as it's the last time we'll welcome Thursday campers to Balado.
"There was a fantastic atmosphere and an incredible buzz amongst the fans.We hope everyone has a great time, and we can't wait to celebrate one final year at Balado with the greatest audience in the world."
There are still tickets available for the three-day event, which includes Biffy Clyro, Calvin Harris, Arctic Monkeys Paolo Nutini and Pharrell Williams.