City chiefs have hiked prices for anyone bringing more than 2000 people to the showcase space.
Their aim is to bring the main square - currently being resurfaced ahead of the Commonwealth Games - into line with other venues.
But, amid concerns they are commercialising the square, officials have also signalled that they will move many product promotions and other marketing events elsewhere.
A spokesman for Glasgow City Council said: "The proposed charges will bring George Square in line with the city's other parks and enable the council to better support events.
"A number of commercial events currently held in the city's parks are excluded from paying hire charges."
The council has also decided that it will shake up rules on who pays what to rent George Square and other city venues.
All commercial operators, for example, can expect to pay while charities and the council's own family of arm's-length companies will get discounts.
The spokesman said: "In these financially challenging times, commercial events will benefit from a clear and uniform approach to charging.
"Community and charity groups will still be able to benefit from a 100% discount for the hire of event spaces."
"Any events planned for this calendar year are exempt from these charges."
The new pricing structure means that while it will be more expensive to stage events for larger groups, George Square will be slightly cheaper to hire for smaller events.
The council made some £200,000 from events at its parks and precincts 2012-13.
That was up from nearly £115,000 in 2008-2009 as the council focuses on events to drive tourism and prop up the city's retail sector.
City parks and public precincts, including George Square, host scores of commercial events every year, and act as billboards to sell everything from the army to soft drinks. They also provide real-life stages for TV shows and films, such as World War Z, the Brad Pitt movie shot last year.
However, figures obtained under Freedom of Information requests show income from hiring out George Square fell last year. The total was just £17,420, not including clear-up costs to the council, in 2012-13. That compares with nearly £40,000 in 2011-12.
Nina Baker, the Green councillor for the city centre, said: "I don't think £1 a day is unreasonable for big events. I am pleased to be reassured that George Square will be used less for promotions and thinks like that."