Parents, grandparents and former staff were joined by opposition councillors and Cathcart SNP MSP, James Dornan, to deliver their opposition to closing St Oswald's secondary.
The group handed in 464 letters objecting to the plan and 112 consultation responses asking for the council to keep the school in its current location.
Glasgow City Council plans to close the school in Cathcart, which has 118 pupils, and move it into St Margaret Mary's in Castlemilk.
The plan is not to integrate the pupils into mainstream classes but to have its own classrooms within the school.
Many parents are concerned about the ability of the children to cope in a mainstream environment, mixing with children from St Margaret Mary's, when they are used to their own school, with its own facilities.
Mr Dornan handed in the submissions to the city Chambers for Stephen Curran, Executive Member for Education.
He said: "This is all about highlighting the strength of feeling among parents and the many concerns they still have."
Mr Dornan said he has no concerns about shared campus schools, but feels this is a closure and wants the parents to be listened to.
He added: "Hopefully their views will be heard and they get the result they are looking for."
The consultation closes this Friday and a decision will be taken once the responses have been considered.
The letters state: "There is a general feeling amongst the parents that not enough information has been given to them in order for this to be a properly informed decision."
Mhairi Hunter, SNP education spokeswoman on Glasgow City Council, said she had heard from many worried parents.
She said: "I do not prejudge what the outcome will be. The council needs to provide reassurance for the well being of the children. I have heard from parents, concerns that this is mainstreaming by the back door. They are valid concerns and the council needs to address them."
A spokeswoman for Glasgow City Council said: "The consultation closes this Friday and we welcome the views of all parents."