The cabinet secretary for health, Alex Neil, has instructed three technical officers to review the two-day breakdown which affected patients attending hospitals in the NHS Great Glasgow and Clyde area, two weeks ago.
They will carry out site visits over three days to look into what caused the glitch, which meant medical staff could not access patient records, and determine whether or not the response was appropriate.
More than 700 patients had appointments cancelled after the system went into meltdown on October 1.
Of this number, 48 cancer patients had their treatment cancelled and at least three operations were postponed.
But the NHS has reassured the public that no patient information was lost.
At a meeting of the NHS GGC board yesterday, chief executive Robert Calderwood said he "personally apologises" to those whose care was interrupted.
He told the meeting: "The cabinet secretary has asked Scottish Government officers to carry out a review of ICT systems across health boards, specifically in relation to NHS Greater Glasgow and Clyde."
The IT experts conducting the review, including a technical officer from the Scottish Government and another from Police Scotland, will report their findings back to the NHS GGC board as well as other health boards across Scotland.
In a report to the meeting, Mr Calderwood said that the IT problems became apparent on the morning on October 1 when staff tried to log on to the system but were met with an "access denied" message.
The software issue, which Mr Calderwood described as "multifactional" and "specific and rare" prompted calls to the UK headquarters of Microsoft from where experts worked with the NHS GGC IT team.
Mr Calderwood commended staff for their work during the two-days and said that all those affected have been contacted and cancer patients whose treatment was cancelled were given alternative appointments within 72 hours.
He added: "Of the 10,700 planned treatments, 10,000 took place as staff reverted to back up systems. There is no evidence of information being lost or patient privacy being breached."
Mr Calderwood said: "I appreciate all clinical staff support and forbearance during the this time as well as IT staff who saw little of their beds and homes during these 48 hours."
Chairman of the health board, Andrew Robertson also thanked staff for their "remarkable resilience".