In her third biennial report for 2011-2013, the director of public health for NHS Greater Glasgow and Clyde describes mental ill-health as "one of the greatest public health challenges of our time".
Dr Linda de Caestecker said many of the health challenges the city faces, such as smoking, drink problems and obesity had their roots in poor mental health.
Glasgow has a 60% higher incidence of self-reported mental health problems than the rest of Scotland, with high levels of depression in women and anxiety in men.
Research has also shown that smokers in Glasgow are the most likely to do so to cope with stress.
Estimates suggest mental health problems contribute to a third of all illness and disability in Scotland.
The report describes how the current economic climate is likely to impact disproportionately on the mental health of the population, compared to other causes of poor health.
It also highlights how stress and pre-natal depression can have an adverse effect on the physical health and brain development of unborn babies.
Dr de Caestecker said pregnant women and women with small children who are experiencing mental health problems would now be prioritised.
She also cites alcohol abuse and poor parenting as other major issues affecting the mental and physical wellbeing of people in Glasgow.
The report emphasises the strong links between physical activity and mental health and the need for a stronger focus on getting people more physically active.
She said: "We need to address some of the wider issues which affect mental health.
"Where we live, how much we earn and the range of amenities in our local area all impact on our health and wellbeing.
"Mental health is key to improving health and wellbeing and reducing inequalities.
"If people have more positive mental health, more confidence, they are much more likely to be able to think about stopping smoking or other unhealthy habits.
"Having a safe, stable nurturing child-parent relationship is a vital protective factor against stresses throughout life.
"It is one of the best health investments a society can make.
"I urge all public agencies and community planning partners to reflect carefully about the impact of mental health when they make decisions about services."
Dr de Caestecker said the board would continue to prioritise the Triple P positive parenting programme, which offers group and individual support to the city's most vulnerable families.
On the issue of alcohol abuse, she said restoring the stigma of drunkenness and recognising the role parents play would go some way to creating a healthier Scotland.
She said: "We need to address the impact of alcohol.
"This starts by making parents better role models."
The report drew on new data from the mental health profile of Greater Glasgow and Clyde developed by the Glasgow Centre for Population Health.