With the new M74 motorway and Commonwealth Games there is more investment in some of the city's poorest communities than ever.
However, bosses at Clyde Gateway, the regeneration company charged with bringing about transformation to benefit local people, said it is a 20-year plan and public sector investment must be sustained over that period.
Clyde Gateway chief executive Ian Manson said the private sector was not willing to put cash into projects unless the public sector was committed to improvements.
He said: "The history of regeneration in the East End is to over-promise and fail to deliver. Clyde Gateway was created to make things happen in an area where nothing happened in 20 years."
Mr Manson told the Scottish Parliament, Local Govern-ment and Regeneration Committee, that his organis-ation's job was to create the physical conditions to bring in outside investment. He said: "The private sector won't invest in sites that have been contaminated for 50 years."
Cleaning up those sites was the priority he said and with the M74 and Commonwealth Games benefits, such as the housing for the athletes' village and rebuilt Dalmar-nock train station, he said regeneration will happen.
MSPs heard how the area's biggest difficulty was ground conditions and Mr Manson said between £70million and £80m was being spent to solve the contamination issues and make the land suitable for investment. He said: "Without that, nothing can happen."
In a written submission to the committee's inquiry into regeneration, Clyde Gateway listed issues that led to East End communities being con-sistently among the country's most deprived. It includes:
l Derelict sites and buildings;
l Poor quality housing;
l Unskilled and poorly educated or trained workforce;
l Health inequalities;
l Lack of employment opportunities;
l Insufficient transport.
Mr Manson said: "The public sector has to demonstrate both confidence and commit-ment to regeneration to satisfy the demands and expectations of the community and of potential investors, who are looking for the clearest indications that the partners will continue to provide long- term backing.
"Our experience with private sector investors is that they are reluctant to invest along-side the public sector when they cannot see a sustained level of commitment."