NHS Greater Glasgow and Clyde yesterday approved the official title for the new £842 million hospital, which will bring the Southern General, the Western Infirmary and the old Victoria Infirmary onto one site with a new children's hospital.
The name was chosen due the campus will have a strong university presence, including the Centre for Stratified Medicine, which aims to develop personalised drugs for patients.
The new children's hospital will keep its existing, official title of The Royal Hospital for Sick Children, losing the decades-old, Yorkhill connection.
Building work at the new hospital is scheduled to be completed on January 26 next year.
After three months of final preparations, services will be transferred on a phased programme from the Western Infirmary, old Victoria Infirmary, Southern General, Yorkhill and the Mansionhouse Unit, until the end of June 2015.
The health board has pledged to honour the Yorkhill name in some way at the new children's hospital, following requests from the public and concerns the name change could impact on fundraising by Yorkhill Children's Charity.
A board statement said: "Requests have been made to give recognition to some historical and significant names within the hospitals involved in the migration.
"This will be discussed with the interested parties."