The 19-year-old will make her debut in front of the Tartan Army before the Scotland v Belgium 2014 World Cup Qualifier.
She'll sing Flower of Scotland to show her support for her national team.
Nina said: "I'm just so pleased to have been invited to sing Flower of Scotland.
"It's a huge honour for any Scottish singer and something I never dreamed I'd have the chance to do.
"It'll be by far the biggest live audience I'll have sung to, so I hope I can lead them in a proper sing along.
"I can't wait to hear the legendary Hampden Roar."
Edinburgh-born Nina shot to fame with singles Stay Out and Way In The World.
And she has been asked to soundtrack the latest John Lewis TV advert, with her take on the Fleetwood Mac classic Don't Stop.
Nina is currently co-producing her debut album after a strings of summer of festival appearances and is looking forward to an 11-date tour in October.
Scotland will run out tonight against top-of-the-table Belgium at Hampden for the 2014 World Cup Qualifier.
It will be only the second time Scotland have met Belgium in a World Cup campaign.