The officers recovered around 240 cannabis plants, with a total street value of £144,000, from the property in Airdrie.
No arrests have been made yet after the operation at the house in Linkwood Road.
Police said an investigation is now under way.
A police spokes-woman said: "Drugs with an estimated street value of £144,000 have been seized in Airdrie.
"Around 10.55am yesterday, officers, acting under warrant, searched a house in Linkwood Road and recovered around 240 cannabis plants."