Officers recovered a large quantity of the class A drug during searches on two houses in Kempsthorn Road, Pollok.
Police raided the two properties at around 5pm yesterday.
Five men, aged 20, 26, 29, 31 and 33, and a 56-year-old woman were arrested and are currently being held in police custody.
Police said a report will be sent to the procurator fiscal.
The five men and one woman are expected to appear at Glasgow Sheriff Court on Monday.