The event will be staged at the Emirates Arena in Glasgow this summer, and the city council believes it will bring around £1.3million to the economy.
The European championships started in 2011 with the inaugural competition held in Prague. Organisers said 34 teams will compete in the two-day event and 5000 people are expected to come to Scotland, including competitors, coaches and family.
Council leader Gordon Matheson said: "The European Cheerleading Union's decision to bring their flagship event to Glasgow is a huge vote of confidence in the city and a real first for Scotland."
The bid to bring the event to Glasgow was made by Scottish cheerleading body Scotcheer and Glasgow City Marketing Bureau. Steve Walls, president of Scotcheer, said: "We are delighted that our bid to bring the 2013 ECU European Cheerleading Championships to Glasgow has been successful and we're now aiming to deliver a show-stopping event."
Cheerleaders from Glasgow's Dance and Cheer Academy will be among the teams competing on June 29 and 30.
Team member Fiona Brown said: "It's a spectacular event, so I'm delighted that this year it's coming to my home city."