The visit, which takes place on Monday, February 24, is part of "Parliament Day Dumbarton", an initiative which takes the parliament and its work out of Holyrood and into local communities across Scotland.
As well as meeting the fictional residents of Shieldinch, the Presiding Officer will meet staff and customers at Café Connect, which employs adults with learning disabilities.
She will also record news stories for Rockvale Rebound, the 'talking newspaper' delivered to local people with visual impairments.
Presiding Officer, the Rt Hon Tricia Marwick MSP, said: "Parliament Day is all about taking the Scottish Parliament out of Edinburgh and into communities across Scotland.
"I am delighted we'll be visiting Dumbarton for our next Parliament Day and I am very much looking forward to meeting local residents and to visiting Café Connect and Rockvale Rebound - two initiatives which contribute so much to the local Dumbarton community.
"It will also be fascinating to see behind the scenes at Shieldinch and to hear about how the establishment of the River City studio in Dumbarton has made an impact locally, particularly in terms of the local economy.
"I hope that by giving the people of Dumbarton a snapshot of the Parliament's work and activities, we will help to build stronger links between the local community and their Parliament."
The Presiding Officer will be accompanied by Jackie Baillie, MSP for Dumbarton, as she visits the set of River City to meet both cast and crew. They will also tour behind the scenes and finding out more about the editing process. During her visit, the Presiding Officer will be briefed on the economic impact of the studio, which employs around 200 people during a year, and has a significant effect on the local economy.
Parliament Day Dumbarton will also involve the Infrastructure and Capital Investment Committee taking evidence on the Housing Bill.
It is an opportunity for people to meet everyone involved with the Parliament: the Presiding Officer, Members, and the staff of the Parliament.