The couples will take part in an experiment to find out if science can produce a stable marriage.
Channel 4's Married At First Sight, based on a hit Danish show, will reduce a pool of 200 people down to six singles willing to say "I do" without having met.
The couples will be matched up by a panel of experts and cameras will follow their first six weeks together.
At the end of filming, they are asked if they want to stay together or go their separate ways.
The channel is also planning documentaries looking at the treatment of dementia and newly-elected police commissioners.
Chief creative officer Jay Hunt said she wanted to build on successful shows including Benefits Street and the coverage of the Winter Paralympics.
She said: "We're taking on Britain's reputation as the divorce capital of Europe in Married At First Sight and in Dementiaville we are exploring innovative research on the treatment of dementia."