Singer Shirley Manson thrilled fans with a special performance to celebrate her success at the awards ceremony held at Glasgow's Old Fruitmarket.
The former Garbage singer was reunited with Martin Metcalfe - who was in the band Goodbye Mr Mackenzie with her - to perform at the glittering evening. It saw her take home the Sir Reo Stakis Foundation Innovation Award.
The evening also featured music from Nina Nesbitt, who received the inaugural Braehead Arena Best Emerging Artist Award, Admiral Fallow and GUN.
Last year, Edinburgh singer-songwriter Nesbitt was a guest at the event and was named as an ambassador for Nordoff-Robbins Music Therapy in Scotland, the charity which organises the fundraiser, and has played an active role in the charity since.
Overnight singing sensation Susan Boyle was among the list of award-winning Scottish acts which included Camera Obscura, Twin Atlantic, Nina Nesbit and Mogwai.
Britain's Got Talent star Edward Reid warmed up the 500-strong audience alongside the Ups and Downs, a Lanarkshire-based theatre group for young people with Down's Syndrome.
They performed their own rendition of Born This Way for an audience of performing artists, celebrities and VIP's.
Reid, who has been a patron for the group for nearly three years, works with them every year as a guest performer for a show that runs for a week each March.
Scottish rap act Stanley Odd, who won 2013's Creative Scotland Big Apple Award to travel to New York with Nordoff-Robbins and perform six gigs over six days during Scotland Week 2013, also took to the stage.
World renowned song-writer John McLaughlin won the Living Legend Award for his accomplishments in song-writing and producing, having worked alongside the likes of Busted, Westlife, 5ive, Lulu, Blue, 911 and Echo and The Bunnymen.
Rose Moon from Grammy winner Adele's management team, who has previously worked for Nordoff-Robbins Scotland and the Scottish Music Awards, won the DWF Biggart Baillie New Boss Award in recognition of her achievements in her career.
Other Nordoff-Robbins Music Therapy in Scotland supporters included Mogwai, who picked up the Ticketmaster Best Live Act Award. The King Tut's Wah Wah Hut Songwriting Award went to Glasgow indie band Camera Obscura for their sixth and most successful album to date.
Twin Atlantic took home the goNORTH Best Breakthrough Act, having headlined the Belladrum festival in Inverness earlier this year.
Now in their 15th year, the awards raise money for Nordoff-Robbins Music Therapy in Scotland, which works with children and adults with disabilities.
The charity combines music and therapy to give a release and a sense of fun for individuals through the power of music. The awards are held each year Glasgow, recently named as the best place in the UK to discover new music talent.
Each week, the city hosts around 130 music events generating £75m for the city's economy each year.
The evening was brought to a thunderous close by Glasgow rock band GUN.
They reformed at the Scottish Music Awards in 2008, and are now back in the studio working on their next album which is set to be released in February 2014.