The Evening Times can reveal more than 400 people have been caught urinating near Ibrox and Parkhead in the last five years.
Official figures show the offence has rocketed around Ibrox Stadium.
There has been a 95% increase in drunken yobs caught urinating in public in four streets around Rangers' ground in the past year.
According to police figures obtained by the Evening Times, a total of 165 tickets for £60 were issued to people caught relieving themselves near Ibrox.
Streets around Celtic Park have also been affected by the scourge of public urinating.
Figures for the offence, usually punished by a fixed penalty notice, show 255 were caught urinating in Parkhead streets.
London Road was by far the East End's urination hotspot, with 83% of offences since 2009/10 taking place there.
Superintendent Thom McLoughlin believes the tactic of hammering "minor offending" is keeping people in Glasgow safe. He has vowed to target drunken yobs who urinate in city streets. He said: "Offences like public urination and street-drinking need to be nipped in the bud early doors.
"I can guarantee those who are stopped for these offences would be the same people who will be involved in violent crime later on in the night.
"Early intervention really is key to making a difference. A £60 fine can sting, but it's better than a jail sentence."
Hotspot areas around Ibrox Stadium include Edmiston Drive, Broomloan Road, Copland Road, and Helen Street.
Between them, they had more than 160 public urination offences in the past five years. In 2012/13, figures reached a four-year low, with 20 incidents recorded.
However, Police Scotland data reveals officers have recorded 39 incidents, in the same area, since April 2013.
Across the city, extra police patrols have been stepped up in anti-social behaviour hotspots.
Incidents around Celtic's ground - including in Kerrydale Street, Janefield Street and Springfield Road - were also recorded.
However, official figures show the offence has fallen by 48% in the last year around Parkhead.
In 2012/13, front-line officers recorded 68 incidents of public urination in the four streets closest to Celtic Park.
That figure dropped to 40 in the last year.