1. Jack the Ripper – Five woman where killed in the Whitechapel district of London’s East End.

2. Tylenol Poisonings – Seven Chicago-area people died from popping Tylenol pills laced with cyanide.

3. Tupac Shakur and the Notorious B.I.G – Tupac was shot leaving five bullet wounds but killer was never identified.

4. Alexander Litvinenko – Became the first person poisoned with polonium, died after a few days later and speculations on who could inflict it was never solved.

5. The Black Dahlia – Actress Elizabeth Short was found dead with her body cut in half but murderer was not found.

6. The Boy in the Box – an unidentified Caucasian male’s body was wrapped in a flannel blanket facing up inside a large cardboard carton.

7. The Boston Strangler – Between 1962 and 1964, thirteen women were strangled with silk stockings.

8. The Monster of Florence – between 1968 and 1985 a killer stalked the streets of Florence, Italy and murdered 16 people.

9. The Alphabet Murders – a series of brutal killings shook the area around Rochester, New York. Victims were all young girls.

10. West Mesa Bone Collector – a dog walker discovered a human bone on what’s known as the West Mesa of Albuquerque, New Mexico.