Tens of thousands of journeys every day start and end at the station taking people to and from work and into the city for leisure and on holiday from all over the country.
The work to electrify the main Glasgow to Edinburgh line will bring reduced journey times and adding longer platforms will allow greater capacity on that route, but that is only one service into Queen Street.
The disruption that any closure would cause on the rest of the city's transport infrastructure would be enormous and closures must be kept to an absolute minimum.
The reassurance from Network Rail that any closure would be in terms of days is welcome and that is what must happen when the work begins in earnest.
Glasgow relies on a transport network of road, rail and air to keep the city connected internally, and externally and to allow commerce to flow.
There are pressures on all aspects of the network and work is required on each to make it as efficient as possible.
One thing is clear - a closure of Queen Street Station would not be welcome news for passengers.