That is not easy to answer before the summer transfer window has closed.
I certainly think it will be between three clubs - Chelsea, Manchester City and Manchester United.
I think that, at the moment, City have the strongest squad. So I will go for them.
But if my old pal Jose Mourinho lands Wayne Rooney then Chelsea can win the title.
If you have a question for Derek, just email him at firstname.lastname@example.org and we'll print the answer alongside the question.