Legia Warsaw beat Aktobe 1-0 in Kazakhstan in their first game since losing their appeal to stay in the Champions League after being kicked out for fielding a suspended player against Celtic.
Ondrej Duda got the Poles' goal.
Cani, Giovani Dos Santos and Mario Gaspar scored as Villarreal won 3-0 in Astana. Adam Maher gave PSV Eindhoven a 1-0 win at home to Shakhtyor of Belarus.
HJK beat Rapid Vienna 2-1 in Finland.
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