The flying full-back will make his first appearance from the bench after undergoing ankle surgery for an injury he picked up on the Scotland summer tour of Australasia.
Now Hoggy is hungry to cut loose in his famous banana boots and put two months of injury frustration to bed.
The Warriors ace said: "It has been a frustrating time but the great thing for me is that I am back quicker than expected.
"I rolled the ankle during the team run for the Samoa Test during the summer and it took a lot of physio to get me to make it.
"I then had a month off and thought that would be enough but when I came back it still wasn't right and surgery was needed. But things have gone well on the rehab and to be back on the bench and for Gregor [Townsend] to have the confidence to put me back in the squad for Zebre tonight is a huge plus.
"It is funny to see so many new faces like Fraser Thomson and Sean Kennedy coming in and getting their chance. It reminds me of when I made my breakthrough last season.
"I am just desperate to get on and play as big a part as I can because I believe the pack we have out will give the backs the type of ball that will allow us to cut loose and I want some of that."
Glasgow head coach Gregor Townsend has made a total of 13 changes for the Italian visit.
There will be a debut at No.8 for former Super XV star Josh Strauss while Fiji scrum-half Nikola Matawalu and Tonga prop Ofa Fainga'anuku are in line to make their debuts for Warriors from the bench.
While former Border Bulldogs centre Byron McGuigan and Scottish Rugby Elite Development players Fraser Thomson and Sean Kennedy also start.
Up front former All Black back-row Angus Macdonald will make his first competitive start for the Warriors at blindside flanker with the team captained by openside Chris Fusaro with club skipper Al Kellock rested.
While Hoggy accepts that Zebre will be determined to put an end to their three-game losing streak in the new side's first tie on Scottish soil, he says that Glasgow's determination to notch a hat-trick of wins will ensure a home win.
The 20-year-old said: "We have responded really well after a difficult start and with so many young guys in there is a real hunger to put down markers for places and underline the level of competition for places that is within the squad.
"You see Josh Strauss coming in at No.8 and he has made a huge impact in training in the last week and I think the Glasgow fans will love him.
"But all our focus has to be on getting a win and trying to produce the type of exciting performance the Glasgow fans will relish."