The Steelmen have shipped back-to-back defeats in the SPL for the first time this campaign in losing to Celtic and then Hearts.
That has seen Well drop seven points off Celtic while also toppling down to sixth.
But with the visit of Pat Fenlon's men followed by a trip to St Johnstone before a home double-header against Dundee United and Dundee, McCall is determined to claim a vital win against the Hibees.
The Well boss, who will be without centre-half Shaun Hutchinson due to a hamstring strain, said: "This is a vital stretch for us with three of our next four games at Fir Park and it is a sequence of fixtures we must take maximum advantage of.
"The importance of home form can never be underestimated and if we can get the win tomorrow night that would be a boost and a platform going to St Johnstone on Saturday week.
"I have no problem with Friday night games and think they do lend themselves to a unique atmosphere.
"Although, I appreciate that the traditionalists among our fans will always prefer Saturday afternoon. But what matters is that we get the positive result we need after the two successive defeats.
"I felt that the loss at Tynecastle was one we did not deserve to suffer and that we were good value for a point and perhaps could have had a penalty.
"But the Hearts game is gone and although our overall performance was reasonable, we need to be creating more clear-cut chances. Hopefully we can do that against Hibs."
Despite also having lost their last two SPL outings to Aberdeen and Ross County, Hibs occupy fourth spot and McCall reckons this is proof of how far they have come under boss Fenlon.
The Well gaffer said: "There is no doubt about the improvement that has gone on under Pat.
"Clearly it was great business for him to tie up James McPake and Leigh Griffiths and they have been a lot more consistent this time around.
"I also rate the Irish lad Gary Deegan, whom they signed from Coventry, while Paul Cairney, who came from Partick, has adjusted well to the SPL.
"But we had a couple of cracking midweek games with them at Fir Park last season with them knocking us out of the Scottish Communities League Cup on penalties and us beating them 4-3 in the SPL.
"That said, the last Friday night game with them was abandoned due to a fire last season so hopefully tomorrow night can go ahead without fuss.
"There is little between teams in the SPL, excluding Celtic, but we can't afford any more negative momentum."