HMS Duncan was due to sail out of the Scotstoun yard this morning for the last time at the start of a delivery voyage to her new home port in Portsmouth.
It's thought the undis-closed fault was found as final preparations got under way several hours before her planned 11.30am departure.
A spokesman for BAE Systems, which owns the two sister warship yards at Scotstoun and Govan, said: "The day’s been cancelled. Duncan won't be leaving. There's a technical fault."
Duncan has been billed as the pride of the Clyde, the last of six Type 45 destroyers to have been built at both yards.
Although the fault has not been made public it is known that the warship could remain at Scotstoun for another two days while engineers fix it.
BAE officials were reluctant to discuss the problem. The defence contractor later released a statement.
It said: "The departure of Duncan from the Clyde has been delayed due to a potential technical issue.
"We are working with the Ministry of Defence to resolve the issue at the earliest opportunity and anticipate the ship will leave the Clyde in the coming days with no significant impact to the programme."
Hundreds of shipyard workers were due to line the Scotstoun quayside to bid the ship farewell. They were to have been joined by Gordon Matheson, leader of Glasgow City Council.
He was the only VIP to have been invited to attend though half the ship's crew including Commanding Officer James Stripe were to have been on board. They were to have been joined by leading BAE engineers.
Duncan is the last of class. The new generation Type 45s represent a £6billion fleet of destroyers built at the Scotstoun and Govan yards to replace the ageing Type 42s.
The first of fleet – HMS Daring was launched seven years ago – and the programme helped swell numbers at both BAE yards from 1200 to more than 3000.
Duncan and her sister ships are the most advanced of their kind in the world and union leaders say the programme triggered unprecedented co-operation between management and the workforce which gave the government confidence in placing a multi-billion pound order for two new aircraft carriers with some of the most intricate work given to the Clyde.
There is now speculation that Duncan will eventually head off to Portsmouth in two days and could still arrive in time to be officially handed over to the Ministry of Defence at a ceremony on Wednesday to be immediately commissioned into the Royal Navy.